Crosslinking Reagents
Cayman Chemical TrIacontnoIc AcId 50mg
An antiallergic agent inhibits IL-4 and IL-5 production in conalbumin-stimulated D10.G4.1 murine Th2 cells in a concentration-dependent manner inhibits ovalbumin-induced increases in eosinophil and total cell numbers as well as IL-4 IL-5 and IL-13 but not IFN-Y levels in BALF in an ovalbumin-sensitized mouse model of asthma at 100 mg/kg inhibits ovalbumin-induced increases in ovalbumin-specific IgE in serum and bronchial hyperresponsiveness to methacholine in the ovalbumin-sensitized mouse model of asthma
Cayman Chemical GIrards Reagent P-d5 50mg
An inhibitor of HCV NS3/4A serine protease a direct-acting inhibitor of hepatitis C virus (HCV)
Cayman Chemical MyrIstelaIdIc AcId 50mg
An active metabolite of nicotine and nAChR agonist induces currents in Xenopus oocytes expressing human a7 nAChRs or a6 subunit-containing nAChRs (EC50s 17 and 3 7 UM respectively) promotes cell migration and destabilizes cell-cell junctions in EA hy926 endothelial cells is self-administered in rats
Cayman Chemical 9-OxonnoIc AcId 50mg
An antagonist of CRTH2/DP2 (IC50 42 nM in a radioligand binding assay) selective for binding to CRTH2/DP2 over DP1 thromboxane and prostacyclin receptors (IC50s 25 6 62 6 and 100 M respectively) inhibits PGD2-induced shape change in human eosinophils (IC50 744 nM)
Cayman Chemical BetulonIc AcId 50mg
An analytical reference standard categorized as a cathinone intended for research and forensic applications
Cayman Chemical DIsuccInImIdyl Glutarate 10mg
An inhibitor of the eIF4F translation initiation complex that inhibits cap-dependent translation with an IC50 value of 4 M reverses tumor chemoresistance in a mouse model of lymphoma by sensitizing cells to the proapoptotic action of DNA damage
Cayman Chemical LIthocholIc AcId 3sulfatS 50mg
An antagonist of sweet taste receptors that blocks the activation of T1R3 by natural and synthetic sweeteners and increases the inhibition of T1R2 by umami compounds used to explore the roles of these receptors in diverse pathways
Cayman Chemical 3 5DIIodothyroacetIc AcId 50mg
A natural neurotransmitter that is activates adrenoceptors (Kis 15 735 and 3970 nM for a1A- B2- and B1-adrenergic receptors respectively) may induce either contraction or relaxation of vascular smooth muscle depending on adrenoceptor subtype expression
Cayman Chemical FusarIc AcId 50mg
A selective serotonin reuptake inhibitor (IC50 1.8 nM for 5-HT reuptake in rat brain synaptosomes) selective for 5-HT reuptake over that of dopamine and norepinephrine (IC50s 6 mM) potentiates 5-hydroxy-L-tryptophan-induced headweaving and tremor in mice (ED50s 0.61 and 0.66 mmol/kg respectively) acts as an antagonist of nicotinic acetylcholine receptors (IC50 0.93 UM)