Crosslinking Reagents
Sigma Aldrich Fine Chemicals Biosciences 3-(Maleimido)propionic acid N-hydroxysuccinimide ester >=98.5% (HPLC) | 55750-62-4 | MFCD00043141 | 100MG
3-(Maleimido)propionic acid N-hydroxysuccinimide ester >=98.5% (HPLC) | Purity: >=98.5% (HPLC) | Mol Wt: 266.21 | 55750-62-4 | MFCD00043141 | 100MG
Cayman Chemical PRfluorohexnsulfonIc AcId 50mg
A perfluoroalkyl substance; activates PPARα in a reporter assay using COS-1 cells expressing the human or mouse receptor from 5-100 µM; has been found in landfill leachate and sea and river water
TARGETMOL CHEMICALS INC SULFO-SMCC SODIUM 200MG
Also available in 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sulfo-SMCC sodium is a commonly used hetero-bifunctional non-cleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups respectively. purity: 99%
Medchemexpress LLC Lys-SMCC-DM1 | 1281816-04-3 | 98.2% | 1103.71 g/mol | C53H75ClN6O15S | 1 MG
Lys-SMCC-DM1 is a lysine-conjugated SMCC-DM1 linker-payload metabolite used in antibody-drug conjugate (ADC) research. It serves as the active metabolite of the DM1 payload and is used as a linker-payload building block and analytical reference for ADC development, characterization, and stability studies. Molecular formula C53H75ClN6O15S; molecular weight 1103.71 g/mol. Store under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month).
- Used as an ADC linker-payload building block and analytical reference.
- Active DM1 metabolite that contributes to tubulin inhibition assays.
- Purified small molecule suitable for conjugation workflows.
- Stable under specified cold-storage conditions when stored under nitrogen.
- Molecular characterization supports analytical method development.
American Research Products Inc Rat soluble cluster of differe
Rat soluble cluster of differentiation 14 sCD14 ELISA Kit from CUSABIO Detection Range 28 ng/mL-1800 ng/mL Sensitivity 7 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Cayman Chemical OrselInIc AcId 50mg
A fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities; scavenges DPPH radicals (IC50 = 5 mM); prevents PAF-induced PARP cleavage in PC12-AC cells and PAF-induced cytotoxicity in Pafr-/-mouse cerebellar granule cells at 1 μg/ml
Cayman Chemical 3-keto UrsolIc AcId 50mg
A triterpenoid with diverse biological activities; inhibits the proliferation of, and colony formation by, MG-63 cells at 10 and 20 µM; inhibits PTP1B and α-glucosidase (IC50s = 11.68 and 61.85 µM, respectively); inhibits glucose- and fructose-induced AGE formation in a cell-free assay at 50 µM; increases glucose uptake in insulin-resistant C2C12 myoblasts at 25, 50, and 100 µM
TARGETMOL CHEMICALS INC Lys-SMCC-DM1 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Lys-SMCC-DM1 (Lys-N-MCC-DM1) is an antibody-drug conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2). It contains the microtubule polymerization inhibitor DM1 as the active metabolite, which inhibits microtubule polymerization. It is commonly used in breast cancer research.
Cayman Chemical ChIcorIc AcId 50mg
A dicaffeoyl ester with diverse biological activities; reduces the viability of Caco-2 and HCT116 colorectal cancer cells from 50-200 μg/ml; inhibits the 3'-processing and DNA integration activities of HIV integrase (IC50s = 1.1 and 0.8 μM, respectively); inhibits HIV entry into H9 cells at 5 μM; oral administration reduces hepatic lipid accumulation, lipid peroxidation, and fibrosis, inhibits production of pro-inflammatory cytokines and activation of NF-kB, and activates the AMPK signaling pathway in a mouse model of NASH induced by a methionine and choline-deficient diet at 10 and 30 mg/kg; reduces blood glucose levels by 54% in mice with streptozotocin-induced diabetes at 2 mg/kg
Cayman Chemical Mc-Val-CIt-PAB 5mg
A peptide linker molecule; used in the synthesis of ADCs; has been used in the synthesis of an ADC containing the tubulin polymerization inhibitor KGP05; has been used as a precursor in the synthesis of Mc-Val-Cit-PABC-PNP
Cayman Chemical QuIlaIc AcId 50mg
A triterpene saponin with diverse biological activities; cytotoxic to SNU-1 and KATO III gastric cancer cells (IC50s = 13.6 and 67 µM, respectively); induces hot plate analgesia in mice (ED50 = 20.7 mg/kg); reduces arachidonic acid- or TPA-induced EAr edema in mice when administered at 0.7 and 1.6 mg/ear, respectively
Medchemexpress LLC Sulfo-SANPAH | 102568-43-4 | MFCD00054986 | 99.8% | 470.41 g/mol | C16H18N6O9S | 5 MG
Sulfo-SANPAH is a heterobifunctional, photo-reactive cross-linker that couples primary amines to surfaces using an N-hydroxysuccinimide (NHS) ester and a UV-activated nitrophenyl azide. It is water-soluble and widely used to immobilize extracellular matrix proteins onto hydrogels and other substrates for cell culture and biomaterials applications.
- Heterobifunctional reagent enabling covalent coupling via an NHS ester and a photoactivated azide.
- Water-soluble sulfonate improves solubility for aqueous surface modification.
- Photoactivation allows spatially controlled immobilization using UV light.
- High purity supports reproducible surface functionalization.
- Suitable for immobilizing extracellular matrix proteins onto hydrogels and biomaterials.